Journal Publications

#: First author
✝: corresponding author
¶: me

  1. Jun-Liszt Li# ¶, Zhanying Bi#, Xingjun Chen#, Tianyue Ming, Baoshan Qiu, Fengzhi Li, Ziyan Feng, Daosheng Ai, Tingting Zhang, Jiayu Wang, Shuai Lin, Yiping Lu, Hu Zhao, Zhanjing Wang, Juan Huang, Fei Zhao, Hu Zhao, Yilong Wang, Wenzhi Sun✝, Woo-ping Ge✝. “A targeted vector for brain endothelial cell gene delivery and cerebrovascular malformation modeling.” Nature Biomedical Engineering (29/10/2025) [PDF | PMID: 41162685 | DOI Link] First author

  2. Huanhuan Pang#, Jun-Liszt Li# ¶, Xiaoling Hu, Fei Chen, Xiaofei Gao, Lauren Zacharias, Ralph Deberardinis, Wenzhi Sun✝, Zeping Hu✝, Woo-Ping Ge✝ “Precision mapping of the mouse brain metabolome.” BioRxiv (28/12/2020) [PDF | Shiny app | DOI Link] Co-first author

    • We are one of the pioneers for method development of spatial metabolomics.

  1. Samuel Lundt#, Nannan Zhang#, Jun-Liszt Li ¶, Zhe Zhang, Xiaowan Wang, Ruisi Bao, Feng Cai, Wenzhi Sun, Woo-Ping Ge, Shinghua Ding✝ “Metabolomic and transcriptional profiling reveals bioenergetic stress and activation of cell death and inflammatory pathways in vivo after neuronal deletion of NAMPT.” Journal of Cerebral Blood Flow & Metabolism (09/02/2021) [PDF | PMID: 33563078 | DOI Link] Second author

    • By RNAseq analysis, we identified the activated downstream gene programs after neuronal deletion of a important enzyme in NAD+ salvage pathway. pub_Nampt_rnaseq

  2. Xiaofei Gao#, Xing-jun Chen#, Meng Ye, Jun-Liszt Li ¶, Nannan Lu, Di Yao, Bo Ci, Fei Chen, Lijun Zheng, Yating Yi, Shiwen Zhang, Zhanying Bi, Xinwei Gao, Yuanlei Yue, Tingbo Li, Jiafu Lin, Ying-Chao Shi, Kaibin Shi, Nicholas E. Propson, Yubin Huang, Katherine Poinsatte, Zhaohuan Zhang, Dale B. Bosco, Shi-bing Yang, Ralf H. Adams, Volkhard Lindner, Fen Huang, Long-Jun Wu, Hui Zheng, Simon Hippenmeyer, Ann M. Stowe, Bo Peng, Marta Margeta, Qingchun Guo, Xiaoqun Wang, Qiang Liu, Jakob Körbelin, Martin Trepel, Hui Lu, Guoen Cai, Bo O. Zhou, Bo Shen, Ying-mei Lu, Wenzhi Sun, Jie-Min Jia, Feng Han, Hu Zhao, Robert M. Bachoo & Woo-ping Ge✝ “Reduction of neuronal activity mediated by blood-vessel regression in the brain.” Nature Communications (01/07/2025) [PDF | PMID: 40595484 | DOI Link]

    • Pre-print version: BioRxiv (15/09/2020) [PDF | DIO Link]
    • Design and Characterization of a brainEC specific Cre driver line: Slco1c1-KI-P2A-iCreERT2
    • By RNAseq analysis, we identified blood vessel regression cause a reduction of neuronal activity due to downregulated of gene cluster pertaining to glutamatergic transmission.

  3. Yihui Wang#, Yue Liang#, Daosheng Ai, Jun-Liszt Li ¶, Ziyan Feng, Zhibao Guo, Xing-jun Chen, Tingting Zhang, Xiaoxiao Zou, Jun-Li Gao, Xiaofei Gao, Xiao-Ling Hu, Long-Jun Wu, Wenzhi Sun, Suiqiang Zhu, Shumin Duan, Wei Wang✝, Woo-ping Ge✝ “ADAM10 mediates macroglial cell fate decisions in the developing brain.” BioRxiv (12/02/2023) [PDF | DOI Link] Under revision in Developmental Cell

    • By RNAseq analysis, We identified a gene program regulated by Adam10 that promote early oligodendrocyte differentiation and repress astrocyte differentiation.
      pub_adam10_rnaseq

  4. Ai, Daosheng#, Baoshan Qiu#, Xing-jun Chen#, Fengzhi Li#, Di Yao, Huijie Mi, Jun-Liszt Li ¶, Bing Zhou, Jian Zuo, Yilong Wang✝, Woo-ping Ge✝, Wenzhi Sun✝ “Inhibition of microglial Slc2a5 attenuates ischemic brain injury.” Metabolism (06/11/2025) [PDF | PMID:41205649 | DIO Link]

  5. Wentong Hong#, Pifang Gong#, Zhonggan Ren#, Xinjie Pan#, Yitong Liu, Guibo Qi, Jun-Liszt Li ¶, Wenzhi Sun, Woo-ping Ge, Chun-Li Zhang, Shumin Duan, Song Qin✝ “Temporal-spatial generation of astrocytes in the developing diencephalon.” Neuroscience bulletin (16/10/2023) [PDF | PMID: 37843774 | DOI Link] Cover story cover_pub_2x

  6. Yating Yi#, Youqi Li#, Shiwen Zhang#, Yi Men#, Yuhong Wang, Jiayi Ding, Qingjie Zhu, Zexi Chen, Xingjun Chen, Jun-Liszt Li ¶, Yilong Wang, Jun Wang, Hanchuan Peng, Li Zhang, Wenjing Luo, Jian Q. Feng, Yongwen He✝, Woo-Ping Ge✝, Hu Zhao✝ “Mapping of individual sensory nerve axons from digits to spinal cord with the Transparent Embedding Solvent System.” Cell Research (03/01/2024) [PDF | PMID: 38168640 | DOI Link] Cover story

    • Research Highlight from Cell Research (03/01/2024): [DOI Link] cover_pub_1x

  7. Tingting Zhang#, Daosheng Ai, Pingli Wei, Ying Xu, Zhanying Bi, Fengfei Ma, Fengzhi Li, Xingjun Chen, Zhaohuan Zhang, Xiaoxiao Zou, Zongpei Guo, Yue Zhao, Jun-Liszt Li ¶, Meng Ye, Ziyan Feng, Xinshuang Zhang, Lijun Zheng, Jie Yu, Chunli Li, Tianqi Tu, Hongkui Zeng, Jianfeng Lei, Hongqi Zhang, Tao Hong, Li Zhang, Benyan Luo, Zhen Li, Chao Xing, Chenxi Jia, Lingjun Li✝, Wenzhi Sun✝, Woo-ping Ge✝ “The subcommissural organ regulates brain development via secreted peptides.” Nature Neuroscience (13/05/2024) [PMID: 38741020 | DOI Link]

    • Pre-print version: BioRxiv (31/03/2024) [PDF | DOI Link]

  8. Jian Ren#, Yazi Huang#, Yeqing Ren#, Tianqi Tu, Baoshan Qiu, Daosheng Ai, Zhanying Bi, Xue Bai, Fengzhi Li, Jun-Liszt Li ¶, Xing-jun Chen, Ziyan Feng, Zongpei Guo, Jianfeng Lei, An Tian, Ziwei Cui, Volkhard Lindner, Ralf H Adams, Yibo Wang, Fei Zhao, Jakob Körbelin, Wenzhi Sun, Yilong Wang, Hongqi Zhang, Tao Hong✝, Woo-ping Ge✝ “Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations.” Brain (30/03/2023) [PDF | PMID: 36995941 | DOI Link]

  9. Lian Liu#, Linzhi Zou#, Kuan Li#, Hanqing Hou, Qun Hu, Shuang Liu, Jie Li, Chenmeng Song, Jiaofeng Chen, Shufeng Wang, Yangzhen Wang, Changri Li, Haibo Du, Jun-Liszt Li ¶, Fangyi Chen, Zhigang Xu, Wenzhi Sun, Qianwen Sun, Wei Xiong✝ “Template-independent genome editing in the Pcdh15av−3j mouse, a model of human DFNB23 nonsyndromic deafness.” Cell Reports (12/07/2022) [PDF | PMID: 35830793 | DOI Link]

    • Pre-print version: BioRxiv (15/11/2020) [PDF | DOI Link]

  10. Beal J, Haddock-Angelli T, Gershater M, de Mora K, Lizarazo M, Hollenhorst J, Randy Rettberg✝,iGEM interlab Study Contributors “Reproducibility of Fluorescent Expression from Engineered Biological Constructs in E. coli.” PLOS One (03/03/2016); 2015 iGEM Interlab Study Contributors: HZAU-China: Pan Chu, Jun Li(Jun-Liszt Li) ¶, Keji Yan [PDF | PMID: 26937966 | DOI Link]

Patents

  1. Wooping Ge, Wenzhi Sun, Jun Li ¶, Zhanying Bi and Xingjun Chen. “Cerebrovascular endothelial cell chimeric promoter, recombinant expression vector, and use.” Under PCT process; Publication Number: WO/2025/082176; International filing date: 26.09.2024; Priority date: 19.10.2023 [WIPO]

  2. Wooping Ge, Wenzhi Sun, Jun Li ¶, Xingjun Chen, Zhanying Bi and Ziyan Feng. “A small molecule, PLX4032, in the preparation of drugs for the treatment of cerebral arteriovenous malformation disease”, Chinese patent, Publication Number: CN119857100; filing date: 26.09.2024; Priority date: 19.10.2023 [WIPO]

Academic Publications

  1. Jun-Liszt Li(Jun Li) (12/2023) A brain vascular endothelial cell targeted gene delivery system based on recombinant AAVs: its development and applications; CIBR; AAIS, Peking University (PhD Thesis)

  2. Jun-Liszt Li(Jun Li) (12/2020) The study of DUSP14 phosphatase underlying sleep need regulation; CIBR; AAIS, Peking University (PhD qualification, research proposal)

  3. Jun-Liszt Li(Jun Li) (06/2018) A cell lethality Reporter(CLR) based system for orphan GPCRs high throughput screening (HTS) and development of novel kinase activity Reporter system; HZAU (Bachelor Thesis)