The VasCode system aims to integrate next-generation sequencing technologies such as whole-exome sequencing and CNV sequencing to identify potential disease-causing gene mutations.

Module 1: VasCode Miner

VasCode Miner is in the upstream of The Big VasCode system, and in charge of mining of disease causing molecular target) The VasCode system aims to integrate next-generation sequencing technologies such as whole-exome sequencing, GWAS, CNV sequencing, scRNAseq to identify potential disease-causing gene mutations.

BrainEC related diseases

  • CCM
  • AVM/bAVM
  • Multiple sclerosis (MS)
  • Cerebral Malaria
  • Stroke
  • Aging

Databases

  • ClinVar: ClinVar is a freely accessible, public archive of reports of human variations classified for diseases and drug responses, with supporting evidence. ClinVar thus facilitates access to and communication about the relationships asserted between human variation and observed conditions, and the history of those assertions.

Module 2: AAV-VasCode system

AAV-VasCode system is in the midstream of The Big VasCode system. We developed a novel technology that combined a series of AAV capsids that has unprecedented power of transduction in different model organisms, like Mouse, Rat, Pig, Marmmoset etc.

Module 3: VasCure drug discovery platform

VasCure is in the downstream of The Big VasCode system. We developed a drug discovery platform for novel theraputic strategy aganist specific brain vascular disease.